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Regulation of Platelet-Derived Growth Factor Gene Expression by Tumor Necrosis Factor and Phorbol Ester in the Human Monocytic Cell Line THP–1

✍ Scribed by MIKIO NAGASHIMA; YOSHIHIRO FUKUO; AKIRA SAITO; MINAMI MATSUI; NOBUO NOMURA; RYOTARO ISHIZAKI; AKIRO TERASHI

Book ID
119865215
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
565 KB
Volume
598
Category
Article
ISSN
0890-6564

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Mutations in the WTI tumor suppressor gene are known t o contribute t o the development of Wilms' tumor (WT) and associated gonadal abnormalities. WTI is expressed principally in the fetal kidney, developing gonads, and spleen and also in the mesothelium, which lines the coelomic cavities. These tis