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Regulation of PC12 cell survival and differentiation by the new P2Y-like receptor GPR17

✍ Scribed by Simona Daniele; Davide Lecca; Maria Letizia Trincavelli; Osele Ciampi; Maria P. Abbracchio; Claudia Martini

Book ID
113528376
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
959 KB
Volume
22
Category
Article
ISSN
0898-6568

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Expression of the new P2Y-like receptor
Expression of the new P2Y-like receptor GPR17 during oligodendrocyte precursor cell maturation regulates sensitivity to ATP-induced death
✍ Stefania Ceruti; Francesca ViganΓ²; Enrica Boda; Silvia Ferrario; Giulia Magni; M πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 955 KB

The P2Y-like receptor GPR17 is expressed by adult neural progenitor cells, suggesting a role in lineage determination. Here, we characterized GPR17 expression and function in mouse cortical primary astrocytes/precursor cell cultures. GPR17 is expressed by a subpopulation of oligodendrocyte precursor