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The P2Y-like GPR17 receptor participates in oligodendrocyte precursor cell reaction in a model of chronic cerebral amyloidosis

✍ Scribed by Boda, Enrica; Hoxha, Eriola; Montarolo, Francesca; Rosa, Patrizia; Abbracchio, Maria Pia; Buffo, Annalisa; Tempia, Filippo

Book ID
122470637
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
43 KB
Volume
5
Category
Article
ISSN
1552-5260

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The P2Y-like receptor GPR17 is expressed by adult neural progenitor cells, suggesting a role in lineage determination. Here, we characterized GPR17 expression and function in mouse cortical primary astrocytes/precursor cell cultures. GPR17 is expressed by a subpopulation of oligodendrocyte precursor