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Regulation of p53 target gene expression by cisplatin-induced extracellular signal-regulated kinase

✍ Scribed by Ryan D. DeHaan; Eugenia M. Yazlovitskaya; Diane L. Persons

Publisher
Springer
Year
2001
Tongue
English
Weight
155 KB
Volume
48
Category
Article
ISSN
0344-5704

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## Abstract Early growth response gene (__Egr‐1__) is a stress response gene activated by various forms of stress and growth factor signaling. We report that supraphysiologic concentrations of O~2~ (hyperoxia) induced Egr‐1 mRNA and protein expression in cultured alveolar epithelial cells, as well