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Regulation of Notch Endosomal Sorting and Signaling by Drosophila Nedd4 Family Proteins

✍ Scribed by Marian B. Wilkin; Ann-Marie Carbery; Maggy Fostier; Hanna Aslam; Sabine L. Mazaleyrat; Jenny Higgs; Anna Myat; Dana A.P. Evans; Michael Cornell; Martin Baron

Book ID
113559193
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
441 KB
Volume
14
Category
Article
ISSN
0960-9822

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## Abstract Ubiquitination is essential in mediating diverse cellular functions including protein degradation and trafficking. Ubiquitin‐protein (E3) ligases determine the substrate specificity of the ubiquitination process. The Nedd4 family of E3 ligases is an evolutionarily conserved family of pr