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Ubiquitination of TrkA by Nedd4-2 regulates receptor lysosomal targeting and mediates receptor signaling

✍ Scribed by Maya V. Georgieva; Yolanda de Pablo; Daniel Sanchis; Joan X. Comella; Marta Llovera


Book ID
111184438
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
793 KB
Volume
117
Category
Article
ISSN
0022-3042

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## Abstract We hypothesized that expression of Toll‐like receptors (TLRs) 2 and 4 by tenocytes is involved in the catabolic processes of tendon degeneration. We investigated TLR2 and TLR4 expression by tenocytes in healthy and tendinotic Achilles tendons. We also investigated whether TLR2 and TLR4