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Regulation of NMDA receptor trafficking

✍ Scribed by Katherine Roche


Book ID
116778032
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
58 KB
Volume
68
Category
Article
ISSN
0168-0102

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Regulation of NMDA receptor trafficking
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Amyloid-b peptide is elevated in the brains of patients with Alzheimer disease and is believed to be causative in the disease process. Amyloid-b reduces glutamatergic transmission and inhibits synaptic plasticity, although the underlying mechanisms are unknown. We found that application of amyloid-b