Regulation of estrogen receptor-α gene e
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Adriana Stoica; Miguel Saceda; Amina Fakhro; Harrison B. Solomon; Bradley D. Fen
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Article
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1999
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John Wiley and Sons
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English
⚖ 205 KB
👁 1 views
This report describes an investigation of the role of 1,25-dihydroxyvitamin D (VD 3 ) in the regulation of estrogen receptor-␣ (ER) in the ER-positive breast cancer cell line, MCF-7. Treatment of cells with 10 nM VD 3 resulted in a 50% decline in the concentration of ER protein at 24 h. Scatchard an