Regulation of low-density-lipoprotein receptors in the human hepatoma cell line Hep G2 : Effect of phorbol 12-myristate 13-acetate and low-density lipoprotein
β Scribed by Jan A. A. M. KAMPS; Theo J. C. VAN BERKEL
- Book ID
- 115129993
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 703 KB
- Volume
- 213
- Category
- Article
- ISSN
- 1432-1327
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Low density lipoprotein (LDL) processing was investigated in a human hepatoma-derived cell line, Hep G2. Hep G2 cells bound, internalized and degraded LDL via a saturable, high affinity (Kd -2 x lo-' M ) pathway similar to that present in other mammalian cells. Although 80% of the uptake and degrada
Low density lipoprotein (LDL) processing was investigated in a human hepatoma-derived cell line, Hep G2. Hep G2 cells bound, internalized and degraded LDL via a saturable, high affinity (Kd -2 x lo-' M ) pathway similar to that present in other mammalian cells. Although 80% of the uptake and degrada