Regulation of chylomicron remnant uptake in the human hepatoma cell-line Hep G2. Role of the low-density lipoprotein receptor
✍ Scribed by Qi Chen; Claes-Henrik Florén; Åke Nilsson; Recaredo Infante
- Book ID
- 115740600
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 434 KB
- Volume
- 1083
- Category
- Article
- ISSN
- 0005-2760
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Low density lipoprotein (LDL) processing was investigated in a human hepatoma-derived cell line, Hep G2. Hep G2 cells bound, internalized and degraded LDL via a saturable, high affinity (Kd -2 x lo-' M ) pathway similar to that present in other mammalian cells. Although 80% of the uptake and degrada
Low density lipoprotein (LDL) processing was investigated in a human hepatoma-derived cell line, Hep G2. Hep G2 cells bound, internalized and degraded LDL via a saturable, high affinity (Kd -2 x lo-' M ) pathway similar to that present in other mammalian cells. Although 80% of the uptake and degrada