Low density lipoprotein (LDL) processing was investigated in a human hepatoma-derived cell line, Hep G2. Hep G2 cells bound, internalized and degraded LDL via a saturable, high affinity (Kd -2 x lo-' M ) pathway similar to that present in other mammalian cells. Although 80% of the uptake and degrada
Regulation of lipoprotein receptors on a rat hepatoma cell line
โ Scribed by Toshitaka Tamai; Wolfgang Patsch; Gustav Schonfeld
- Book ID
- 118896121
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 930 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0021-9150
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Low density lipoprotein (LDL) processing was investigated in a human hepatoma-derived cell line, Hep G2. Hep G2 cells bound, internalized and degraded LDL via a saturable, high affinity (Kd -2 x lo-' M ) pathway similar to that present in other mammalian cells. Although 80% of the uptake and degrada
The responsiveness of low density lipoprotein (LDL) binding and uptake was measured in a human hepatoblastoma cell line, Hep G2. These cells exhibited both saturable, high-affinity and nonsaturable low-affinity components similar to that described for LDL binding in other mammalian cells. In additio