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Regulation of Leukotriene-Biosynthetic Enzymes During Differentiation of Myelocytic HL-60 Cells to Eosinophilic or Neutrophilic Cells

โœ Scribed by Kylie A. Scoggan; Donald W. Nicholson; Anthony W. Ford-Hutchinson


Book ID
115132155
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
893 KB
Volume
239
Category
Article
ISSN
1432-1327

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Neutrophils express functional toll-like receptor2 (TLR2) and 4 (TLR4) that are crucial for the production of inflammatory cytokines. Here, we show that dimethylsulfoxide-induced neutrophil-like differentiation of promyelocytic HL-60 cells (dHL-60) results in cells that respond to TLR2 and TLR4 liga