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Regulation of Interleukin-6 Production by Prostaglandin E2 in Fetal Rat Osteoblasts: Role of Protein Kinase A Signaling Pathway

✍ Scribed by Isabelle Millet; Thomas L. Mccarthy; AgnÈS Vignery


Book ID
111486355
Publisher
American Society for Bone and Mineral Research
Year
1998
Tongue
English
Weight
378 KB
Volume
13
Category
Article
ISSN
0884-0431

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## Abstract Inhibition of osteoblast‐mediated mineralization is one of the major catabolic effects of parathyroid hormone (PTH) on bone. Previously, we showed that PTH induces matrix γ‐carboxyglutamic acid (Gla) protein (MGP) expression and established that this induction is critical for PTH‐mediat