## Abstract Thymic epithelial cells (TEC) form the structural and functional microenvironment necessary for the establishment and quality control of the T cell repertoire. In addition, they provide an ectopic source of numerous tissue‐restricted antigens (TRA), a feature called promiscuous gene exp
Regulation of insulin gene expression by cytokines and cell–cell interactions in mouse medullary thymic epithelial cells
✍ Scribed by D. Levi; C. Polychronakos
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 183 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0012-186X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Glucose and insulin are generally considered to express opposite effects on insulin synthesis and secretion from pancreatic islets. For the most part this generalization has arisen from short-term experiments. Our studies focused on the chronic, long-term effects of variable insulin concentrations o
## Abstract We previously identified an Ets cis‐element in the mouse caveolin‐1 promoter that is selectively activated in lung epithelial (E10), but not lung endothelial murine lung endothelial cell line (MFLM‐4), cell lines and therefore appears important for differential, cell‐specific caveolin‐1
Because of its prominent expression in central nervous system inflammatory pathology by astrocytes, we examined the mechanism of human IP-10 (hIP-10) gene induction by interferon-gamma (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha) in astrocytoma cells. When present together, IFN-gamma and