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Regulation of 4-1BB expression by cell-cell interactions and the cytokines, interleukin-2 and interleukin-4

✍ Scribed by Karen E. Pollok; Seung H. Kim; Byoung S. Kwon

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
803 KB
Volume
25
Category
Article
ISSN
0014-2980

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## Abstract The growth‐inhibitory effect of interleukin‐4 (IL‐4) was investigated in a panel of 7 human colorectal‐carcinoma cell lines. In 5 cell lines (HT29, WiDr, LS41 IN, LS513, LS1034) a dosedependent reduction of proliferation was documented. At 100 U/ml, IL‐4 inhibited thymidine incorporatio