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Regulation of Ins(1,4,5)P3 receptor isoforms by endogenous modulators

✍ Scribed by Edwin C Thrower; Robert E Hagar; Barbara E Ehrlich


Book ID
117340657
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
126 KB
Volume
22
Category
Article
ISSN
0165-6147

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Fluorinated Analogs of Ins(1,4,5)P3
✍ James F. Marecek; Glenn D. Prestwich πŸ“‚ Article πŸ“… 1989 πŸ› Elsevier Science 🌐 French βš– 248 KB

2-Fluoro-2-deoxy-lns(1,4,5)Ps (2) and 2,2-difluoro-Z-deoxy-Ins(l,4,5)P, (3) were synthesized from protected inositol precursors. The monofluoro compound with free 3,6-hydroxyl groups underwent slow defluorination at pH 1 13, as determined by laF-NMR, while the difluoro compound was inert. Cells can