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Ins(1,4,5)P3 receptor regulation during ‘quantal’ Ca2+ release in smooth muscle

✍ Scribed by John G. McCarron; Marnie L. Olson; Richard D. Rainbow; Debbi MacMillan; Susan Chalmers

Book ID
116918718
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
933 KB
Volume
28
Category
Article
ISSN
0165-6147

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## Abstract PRIP‐1 was isolated as a novel inositol 1,4,5‐trisphosphate [Ins(1,4,5)P~3~] binding protein with a domain organization similar to phospholipase C‐δ1 (PLC‐δ1) but lacking the enzymatic activity. Further studies revealed that the pleckstrin homology (PH) domain of PRIP‐1 is the region re