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Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation

✍ Scribed by Veerle Vanderheyden; Benoit Devogelaere; Ludwig Missiaen; Humbert De Smedt; Geert Bultynck; Jan B. Parys

Book ID: 113486254
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 529 KB
Volume: 1793
Category: Article
ISSN: 0167-4889
DOI: 10.1016/j.bbamcr.2008.12.003

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## Abstract The inositol 1,4,5‐trisphosphate receptor (IP~3~R), a ligand‐gated Ca^2+^ channel, is the main regulator of intracellular Ca^2+^ mobilization in non‐excitable cells. An emerging body of evidence suggests that specific regulatory control of the Ca^2+^ signaling pathway is modulated by th