Calcium-dependent immediate feedback control of inositol 1,4,5-trisphosphate-induced Ca2+ release
โ Scribed by Iino, Masamitsu; Endo, Makoto
- Book ID
- 109782287
- Publisher
- Nature Publishing Group
- Year
- 1992
- Tongue
- English
- Weight
- 331 KB
- Volume
- 360
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/360076a0
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๐ SIMILAR VOLUMES
We have studied arginine vasopressin (AVP)-, thapsigarginand inositol 1,4,5trisphosphate (InsPJ-mediated CaL+ release in renal epithelial LLC-PK, cells. AVP-induced changes in the intracellular free calcium concentration ([Ca"],) were studied in indo-1 loaded single cells by confocal laser cytometry
## Abstract In nonโexcitable cells, the inositol 1,4,5โtrisphosphate receptor (IP~3~R), a ligandโgated Ca^2+^ channel, plays an important role in the control of intracellular Ca^2+^. There are three subtypes of IP~3~R that are differentially distributed among cell types. AR4โ2J cells express almost