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REGULATION OF IMMUNE RESPONSES BY TGF-β*

✍ Scribed by Letterio, John J.; Roberts, Anita B.

Book ID: 120060483
Publisher: Annual Reviews
Year: 1998
Tongue: English
Weight: 265 KB
Volume: 16
Category: Article
ISSN: 0732-0582
DOI: 10.1146/annurev.immunol.16.1.137

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## Abstract Transforming growth factor‐β (TGF‐β) responsiveness in cultured cells can be modulated by TGF‐β partitioning between lipid raft/caveolae‐ and clathrin‐mediated endocytosis pathways. The TβR‐II/TβR‐I binding ratio of TGF‐β on the cell surface has recently been found to be a signal that c