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Regulation of human interferon production stimulated with poly(I) · Poly(C): Correlation between shutoff and hyporesponsiveness to reinduction

✍ Scribed by Masayoshi Kohase; Jan Vilček

Book ID: 119009489
Publisher: Elsevier Science
Year: 1977
Tongue: English
Weight: 710 KB
Volume: 76
Category: Article
ISSN: 0042-6822
DOI: 10.1016/0042-6822(77)90280-x

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## Abstract The interferon‐inducer, polyinosinate. Polycyctidylate [Poly (I). Poly (C)] stimulated both prostaglandin E (PGE) and hyaluronic acid (HA) production by human cultured synovial fibroblasts. Increased accumulation of PGE in the medium was noted within 3 hours of culture, while accumulati