Regulation of human cardiac KCNQ1/KCNE1 channel by epidermal growth factor receptor kinase
β Scribed by Ming-Qing Dong; Hai-Ying Sun; Qiang Tang; Hung-Fat Tse; Chu-Pak Lau; Gui-Rong Li
- Book ID
- 116274949
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 765 KB
- Volume
- 1798
- Category
- Article
- ISSN
- 0005-2736
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## Abstract ## BACKGROUND It was recently shown that neuropilinβ1 (NRPβ1), which was described originally as a receptor for the semaphorins/collapsins (ligands involved in neuronal guidance), is a coreceptor for vascular endothelial growth factor (VEGF) and increases the affinity of specific isofo
The receptor for epidermal growth factor (EGF) is a glycosylated transmembrane phosphoprotein that exhibits EGF-stimulable protein tyrosine kinase activity. On EGF stimulation, the receptor undergoes a self-phosphorylation reaction at tyrosine residues located primarily in the extreme carboxyl-termi