Regulation of cardiac adenylyl cyclase by Epidermal Growth Factor (EGF): Role of EGF receptor protein tyrosine kinase activity
β Scribed by Bipin G. Nair; Tarun B. Patel
- Book ID
- 115783477
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 917 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0006-2952
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## Abstract The capacity of cultured human fibroblasts to bind ^125^Iβlabeled epidermal growth factor (EGF) was measured during protein synthesis inhibition and reinitiation. Protein synthesis was inhibited by incubation of human fibroblasts in histidineβfree medium supplemented with Lβhistidinol t
Normal rat kidney (NRK) fibroblasts are immortalized cells that are strictly dependent on externally added growth factors for proliferation. When cultured in the presence of epidermal growth factor (EGF) as the only growth stimulating hormone, these cells have a normal phenotype and undergo density-