Regulation of histone acetylation during meiotic maturation in mouse oocytes
โ Scribed by Tomohiko Akiyama; Jin-Moon Kim; Masao Nagata; Fugaku Aoki
- Book ID
- 111663698
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 198 KB
- Volume
- 69
- Category
- Article
- ISSN
- 1040-452X
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The developmental capacity of oocytes matured in vitro following isolation at the germinal vesicle stage from freshly killed mice (control) was compared with that of oocytes isolated from the carcasses of mice killed 3, 6, 9, and 12 hr earlier. The yield of intact, cumulus cell-enclosed oocytes decr
## Abstract Mouse oocytes spontaneously undergo meiotic maturation when removed from the ovary and cultured in vitro. This paper describes the changes in cell surface membrane potential from the germinal vesicle (GV) stage (โ 46 mV, inside negative), through germinal vesicle breakdown (GVBD) (โ 31