Induction of meiotic maturation in mouse oocytes by adenosine analogs
โ Scribed by Stephen M. Downs; Jing Chen
- Book ID
- 111663987
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 211 KB
- Volume
- 73
- Category
- Article
- ISSN
- 1040-452X
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๐ SIMILAR VOLUMES
Maturation-promoting factor (MPF) has been known to be produced in the cytoplasm of starfish and amphibian oocytes, where it triggers meiotic maturation. Cytoplasm obtained from maturing oocytes of either mouse or surf clam was found to induce maturation when injected into immature starfish oocytes.
The developmental capacity of oocytes matured in vitro following isolation at the germinal vesicle stage from freshly killed mice (control) was compared with that of oocytes isolated from the carcasses of mice killed 3, 6, 9, and 12 hr earlier. The yield of intact, cumulus cell-enclosed oocytes decr