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Regulation of heme metabolism and cytochrome p-450 levels in primary culture of rat hepatocytes in a defined medium

โœ Scribed by Ritva P. Evarts; Elizabeth Marsden; Snorri S. Thorgeirsson

Book ID
115777568
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
559 KB
Volume
33
Category
Article
ISSN
0006-2952

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The aim of this study was to test suitable culture conditions for maintaining normal cellular cytoarchitecture and inducibility of P450 enzymes in primary cultures of human hepatocytes by prototypical inducers. The selectivity and sensitivity of a sandwich culture system were determined by treating