๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

REGULATION OF GENE EXPRESSION BY GC-RICH DNA CIS -ELEMENTS

โœ Scribed by Janet P. Hapgood; Johann Riedemann; Sonja D. Scherer


Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
240 KB
Volume
25
Category
Article
ISSN
1065-6995

No coin nor oath required. For personal study only.

โœฆ Synopsis


Abstract

GCโ€rich DNA cis elements are important transcriptional regulatory elements present in the promoter, enhancer and locus control regions of many eukaryotic genes from several species. This review attempts to examine the structure, function and biological significance of GCโ€rich cis โ€regulatory elements and their cognate binding proteins, with a view to understanding their role in regulation of gene expression.


๐Ÿ“œ SIMILAR VOLUMES


Cell-type-specific expression of mouse D
โœ Masamitsu Yamaguchi; Yuko Hayashi; Kozo Ajiro; Akio Matsukage ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 564 KB

Nagoya 464, lapdn RNA blot hybridization analysis revealed that the steady-state level of DNA polymerase p-mRNA in mouse neuroblastoma N.1 OTG2 cells was approximately fivefold higher than that in NIHIIT3 cells. In order to examine the function of DNA polymerase p-gene silencers in these two cell li

Identification of cis-element regulating
โœ Hideyo Ohuchi; Akihiro Yasue; Katsuhiko Ono; Shunsuke Sasaoka; Sayuri Tomonari; ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 578 KB

Fibroblast growth factor (FGF) signaling is crucial for the induction and growth of the ear, a sensory organ that involves intimate tissue interactions. Here, we report the abnormality of Fgf10 null ear and the identification of a cis-regulatory element directing otic expression of Fgf10. In Fgf10 n

Extinction of the human insulin gene exp
โœ Corinne Besnard; Eliane Monthioux; Patrick Lorร s; Jacques Jami; Dominique Daegel ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 795 KB

## Abstract Insulin gene expression in rat insulinoma (RIN) cells is extinct in RIN ร— fibroblast hybrids and can reappear upon loss of DNA contributed by the fibroblast parent. (Besnard et al., Exp. Cell Res. __185:__101โ€“108, 1989). In the present study, we looked for the role of 5โ€ฒโ€flanking sequen

Light-regulated expression of the pea pl
โœ Chris Helliwell; Carl Webster; John Gray ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 342 KB

Expression of the pea plastocyanin gene (__PetE__) is regulated by light in both pea and transgenic tobacco plants. However, the __PetE__ promoter with the 5โ€ฒ untranslated leader region does not direct lightโ€regulated expression of the GUS reporter gene in transgenic tobacco. This suggested that seq

A cysteine-rich LIM-only protein mediate
โœ Tong Zhang; Shunhui Zhuang; Darren E Casteel; Renate B Pilz ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› BioMed Central ๐ŸŒ English โš– 192 KB

Vascular smooth muscle cells can reversibly change from a differentiated, contractile to a de-differentiated, synthetic phenotype; de-differentiation correlates with decreased expression of smooth muscle (SM)-specific genes and loss of cGMP-dependent protein kinase (PKG), and transfection of PKG int

Epigenetic regulation of metallothionein
โœ Sarmila Majumder; Huban Kutay; Jharna Datta; Dennis Summers; Samson T. Jacob; Ka ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 623 KB

## Abstract Metallothioneins (MTs) are a group of cysteineโ€rich stress response proteins that scavenge reactive oxygen species and heavy metals. Recently, we have shown that MTโ€I promoter is methylated and suppressed in some solid and liquid tumors and can be robustly activated following treatment