Nagoya 464, lapdn RNA blot hybridization analysis revealed that the steady-state level of DNA polymerase p-mRNA in mouse neuroblastoma N.1 OTG2 cells was approximately fivefold higher than that in NIHIIT3 cells. In order to examine the function of DNA polymerase p-gene silencers in these two cell li
REGULATION OF GENE EXPRESSION BY GC-RICH DNA CIS -ELEMENTS
โ Scribed by Janet P. Hapgood; Johann Riedemann; Sonja D. Scherer
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 240 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1065-6995
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
GCโrich DNA cis elements are important transcriptional regulatory elements present in the promoter, enhancer and locus control regions of many eukaryotic genes from several species. This review attempts to examine the structure, function and biological significance of GCโrich cis โregulatory elements and their cognate binding proteins, with a view to understanding their role in regulation of gene expression.
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