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Regulation of cyclooxygenase-1 and -2 in knockout cells and mice

✍ Scribed by Leslie R. Ballou

Book ID
114101181
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
56 KB
Volume
59
Category
Article
ISSN
0090-6980

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## Abstract As with cyclooxygenase (COX)‐2, genetic disruption of __COX‐1__ gene or pharmacologic inhibition of its activity has been shown to decrease the number of intestinal polyps in __Apc__ gene‐deficient mice. The present study was designed to investigate the combined effects of COX‐1 and COX