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Regulation of cholesterol biosynthesis and cancer signaling

โœ Scribed by Gorin, Andrey; Gabitova, Linara; Astsaturov, Igor

Book ID
119221873
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
320 KB
Volume
12
Category
Article
ISSN
1471-4892

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Mammalian cells require cholesterol for proliferation. Cholesterol contributes not only to the physicochemical properties of membranes but also to the organization of lipid rafts involved in signal transduction. Inhibition of cholesterol biosynthesis from lanosterol results in the inhibition of cell