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Post-lanosterol biosynthesis of cholesterol and cancer

✍ Scribed by Lasunción, Miguel A; Martín-Sánchez, Covadonga; Canfrán-Duque, Alberto; Busto, Rebeca


Book ID
119221875
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
261 KB
Volume
12
Category
Article
ISSN
1471-4892

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Post-lanosterol biosynthesis of choleste
✍ Lasunción, Miguel A; Martín-Sánchez, Covadonga; Canfrán-Duque, Alberto; Busto, R 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 261 KB

Mammalian cells require cholesterol for proliferation. Cholesterol contributes not only to the physicochemical properties of membranes but also to the organization of lipid rafts involved in signal transduction. Inhibition of cholesterol biosynthesis from lanosterol results in the inhibition of cell