Post-lanosterol biosynthesis of choleste
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Lasunción, Miguel A; Martín-Sánchez, Covadonga; Canfrán-Duque, Alberto; Busto, R
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Article
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2012
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Elsevier Science
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English
⚖ 261 KB
Mammalian cells require cholesterol for proliferation. Cholesterol contributes not only to the physicochemical properties of membranes but also to the organization of lipid rafts involved in signal transduction. Inhibition of cholesterol biosynthesis from lanosterol results in the inhibition of cell