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Regulation of cell lineage specification by the retinoblastoma tumor suppressor

✍ Scribed by Skapek, S X; Pan, Y-R; Lee, E Y-H P

Book ID
110070727
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
202 KB
Volume
25
Category
Article
ISSN
0950-9232

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## Abstract High‐risk human papilloma virus (HPV) encodes two oncoproteins, E6 and E7, which are vital to viral replication and contribute to the development of cervical cancer. HPV16 E7 can target over 20 cellular proteins, but is best known for inactivating the retinoblastoma (RB) tumor suppresso