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Regulation of cell death signaling by sorafenib in hepatocellular carcinoma. role of p53 gene family members

✍ Scribed by De la Rosa, A.J.; Lovas, A.; Müller, M.; Padillo, F.J.; Muntané, J.

Book ID
123520216
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
55 KB
Volume
65
Category
Article
ISSN
0891-5849

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✍ Ikue Fukuda; Katsuhiro Ogawa 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 585 KB

## Abstract Structural alterations of the __p53__ gene were investigated in chemically induced rat hepatocellular carcinomas (HCCs), hyperplastic hepatic nodules (HPNs), and cell lines derived from rat neoplastic and normal liver cells. The mutations were detected by GC‐clamped denaturing gradient