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Regulation of cancer invasion and vascularization by plasminogen activator inhibitor-1

✍ Scribed by A. Noël; K. Bajou; V. Masson; L. Devy; F. Frankenne; J.M. Rakic; V. Lambert; P. Carmeliet; J.M. Foidart

Book ID
117836945
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
146 KB
Volume
13
Category
Article
ISSN
0268-9499

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## Abstract Although originally known as a plasma serine protease involved in clot dissolution, tPA and its primary inhibitor, PAI‐1, play crucial roles in synaptic reorganization and plasticity in the central nervous system. In contrast to the wide array of work conducted in neural cells, relative