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Regulation of cancer cell migration and bone metastasis by RANKL

✍ Scribed by Jones, D. Holstead; Nakashima, Tomoki; Sanchez, Otto H.; Kozieradzki, Ivona; Komarova, Svetlana V.; Sarosi, Ildiko; Morony, Sean; Rubin, Evelyn; Sarao, Renu; Hojilla, Carlo V.

Book ID
109895631
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
431 KB
Volume
440
Category
Article
ISSN
0028-0836

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## Abstract Invasion of distant tissues by tumor cells is the primary cause of therapeutic failure in the treatment of malignant lung cancer cells. Receptor activator of nuclear factor‐κB ligand (RANKL) and its receptor, RANK, play a key role in osteoclastogenesis and tumor metastasis. Intercellula