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Regulation of Breast Cancer Metastasis by IGF Signaling

✍ Scribed by Deepali Sachdev


Publisher
Springer US
Year
2008
Tongue
English
Weight
225 KB
Volume
13
Category
Article
ISSN
1083-3021

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## Abstract Breast cancer metastasis suppressor 1 (BRMS1) suppresses metastasis of multiple tumor types without blocking tumorigenesis. BRMS1 forms complexes with SIN3, histone deacetylases and selected transcription factors that modify metastasis‐associated gene expression (__e.g__., EGFR, OPN, PI