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Regulation of brain endothelial cells migration and angiogenesis by P-glycoprotein/caveolin-1 interaction

✍ Scribed by Stéphane Barakat; Sandra Turcotte; Michel Demeule; Marie-Paule Lachambre; Anthony Régina; Loris G. Baggetto; Richard Béliveau

Book ID
116296850
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
606 KB
Volume
372
Category
Article
ISSN
0006-291X

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## Abstract A major concern regarding the chronic administration of antiretroviral drugs is the potential for induction of drug efflux transporter expression (i.e., P‐glycoprotein, P‐gp) at tissue sites that can significantly affect drug distribution and treatment efficacy. Previous data have shown