Regulation of GTP cyclohydrolase I gene
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Jude Al Sarraj; Charles Vinson; Jiahuai Han; Gerald Thiel
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Article
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2005
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John Wiley and Sons
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English
β 367 KB
## Abstract Tetrahydrobiopterin is an essential cofactor for the phenylalanine, tyrosine and tryptophan hydroxylases, and the family of nitric oxide synthases. The initial and rateβlimiting enzyme in the biosynthesis of tetrahydrobiopterin is GTP cyclohydrolase I. The proximal promoter of the human