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Regulation of aromatase and 5α-reductase by 25-hydroxyvitamin D3, 1α,25-dihydroxyvitamin D3, dexamethasone and progesterone in prostate cancer cells

✍ Scribed by Yan-Ru Lou; Teemu Murtola; Pentti Tuohimaa

Book ID
116697574
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
154 KB
Volume
94
Category
Article
ISSN
0960-0760

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Differentiating and antitumor activities
Differentiating and antitumor activities of 1α,25-dihydroxyvitamin D3 in vitro and 1α-hydroxyvitamin D3 in vivo on human osteosarcoma
✍ Dr. Hiroyuki Tsuchiya; Hajime Morishita; Katsuro Tomita; Yoshimichi Ueda; Motohi 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 813 KB

## Abstract The differentiating and antitumor activities of 1α,25‐dihydroxyvitamin D~3~ (1α,25(OH)~2~D~3~) in vitro and 1α‐hydroxyvitamin D~3~ (1α(OH)D~3~) in vivo were studied with a human osteosarcoma cell line (OST strain). Antitumor activity was estimated with the use of 3‐(4,5‐dimethylthiazol)