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Regulation of arachidonic acid turnover by 1,25-(OH)2D3 and 24,25-(OH)2D3 in growth zone and resting zone chondrocyte cultures

✍ Scribed by Z. Schwartz; L.D. Swain; V. Ramirez; B.D. Boyan

Book ID: 115729499
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 907 KB
Volume: 1027
Category: Article
ISSN: 0005-2736
DOI: 10.1016/0005-2736(90)90319-j

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Prior studies have shown that 24,25-(OH) 2 D 3 and 1,25-(OH) 2 D 3 regulate protein kinase C (PKC) in costochondral chondrocytes in a cell maturation-dependent manner, with 1,25-(OH) 2 D 3 affecting primarily growth zone (GC) cells and 24,25-(OH) 2 D 3 affecting primarily resting zone (RC) cells. In