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Regulation of androgen receptor mRNA and protein level by steroid hormones in human mammary cancer cells

✍ Scribed by Hackenberg, Reinhard; Hawighorst, Thomas; Filmer, Angelika; Slater, Emily P.; Bock, Karin; Beato, Miguel; Schulz, Klaus-Dieter

Book ID
123080283
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
1013 KB
Volume
43
Category
Article
ISSN
0960-0760

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Although the androgen receptor (AR) has been detected by ligand-binding assays, there is little known about the expression and regulation of the AR gene in human breast-cancer cells. AR mRNA, measured by Northern analysis in 18 cell lines, was found to be expressed predominantly in oestrogen-and pro