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Regulation of 5-phosphoribosyl-1-pyrophosphate synthesis in human fibroblasts by the concentration of inorganic phosphate

โœ Scribed by RAIVIO, K; LAZAR, C; BECKER, M


Book ID
122685319
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
535 KB
Volume
678
Category
Article
ISSN
0304-4165

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The properties of an assay for the 5-phosphoribosyl-1-pyrophosphate (PRPP) content of cultured mammalian fibroblasts are described. The assay is based upon the PRPP-dependent release of "CO, from [carboxy/-"Clorotic acid by a commercially available preparation of yeast orotidine-5'-monophosphate pyr