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Regulation of 5-lipoxygenase enzyme activity

✍ Scribed by Olof Rådmark; Bengt Samuelsson

Book ID
116291144
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
219 KB
Volume
338
Category
Article
ISSN
0006-291X

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Dimethyleicosatrienoic acids: Inhibitors
Dimethyleicosatrienoic acids: Inhibitors of the 5-lipoxygenase enzyme
✍ Carl D. Perchonock; Joseph A. Finkelstein; Irene Uzinskas; John G. Gleason; Henr 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 190 KB

Syntheses of 7,7-and 10,10-dimethyleicosa-5(Z1,8(Z),ll(Z1-trienoic acids (zand $1, which possess 5-lipoxygenase inhibitory activity, are described. Arachidonic acid (L) is now well established as a key substance in the biosynthesis of the leukotrienes, a family of compounds that have been implicated