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Regulation of 17β-hydroxysteroid dehydrogenase in a newly-established human breast carcinoma cell line

✍ Scribed by Mehta, Rajeshwari R.; Das Gupta, Tapas K.

Book ID: 123262595
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 590 KB
Volume: 46
Category: Article
ISSN: 0960-0760
DOI: 10.1016/0960-0760(93)90190-8

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## Abstract Steroid regulation of 17β‐hydroxysteroid dehydrogenase (17‐HSD) was studied in the T‐47D human breast‐cancer cell line, using a radioimmunoassay. In addition, 3 mRNA species (2.4, 1.4, and 0.9 kb) specific for the enzyme were shown to be present in these cells. All the synthetic progest