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Regulation by hypoxia of methionine adenosyltransferase activity and gene expression in rat hepatocytes

✍ Scribed by Matias A. Avila; M.Victoria Carretero; E.Nelson Rodriguez; Jose M. Mato

Book ID
118520439
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
273 KB
Volume
114
Category
Article
ISSN
0016-5085

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Liver-specific and non-liver-specific methionine adenosyltransferase (MAT) are products of two genes, MAT1A and MAT2A, respectively, that catalyze the formation of S-adenosylmethionine (SAM), the principal methyl donor. Mature liver expresses mainly MAT1A. We showed a switch from MAT1A to MAT2A gene