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In vivo regulation by glutathione of methionine adenosyltransferase S-nitrosylation in rat liver

✍ Scribed by Fernando J Corrales; Félix Ruiz; José M Mato

Book ID
118569103
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
969 KB
Volume
31
Category
Article
ISSN
0168-8278

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Nitric oxide inactivates rat hepatic met
Nitric oxide inactivates rat hepatic methionine adenosyltransferase in vivo by S-nitrosylation
✍ Félix Ruiz; Fernando J. Corrales; Carmen Miqueo; José M. Mato 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB

We investigated the mechanism of nitric oxide (NO) action on hepatic methionine adenosyltransferase (MAT) activity using S-nitrosoglutathione (GSNO) as NO donor. Hepatic MAT plays an essential role in the metabolism of methionine, converting this amino acid into S-adenosylmethionine. Hepatic MAT exi