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Regulation by 1α,25-dihydroxyvitamin D3 of expression of stanniocalcin messages in the rat kidney and ovary

✍ Scribed by Shinji Honda; Masahide Kashiwagi; Kayoko Ookata; Akihiro Tojo; Shigehisa Hirose

Book ID
117111476
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
170 KB
Volume
459
Category
Article
ISSN
0014-5793

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Bony fish use the glycoprotein hormone stanniocalcin (STC) to counteract hypercalcaemia. This is achieved through dual mechanisms involving gill calcium uptake inhibition and stimulation of renal inorganic phosphate reabsorption. Human STC (hSTC-1) shows considerable homology with both rat and mouse