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Regulation by 1,25-dihydroxyvitamin D3 1,25(OH)2D3 of preproparathyroid hormone mRNA in vivo

✍ Scribed by Silver, Justin; Naveh, Tally; Mayer, Hubert; Mayer, Hans; Popovtzer, Mordecai M.


Book ID
122540105
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
146 KB
Volume
7
Category
Article
ISSN
8756-3282

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## Abstract The 25‐hydroxyvitamin D~3~‐24‐hydroxylase mRNA is tightly and reciprocally regulated by 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) and parathyroid hormone (PTH). The upregulation of the 24‐hydroxylase by 1,25(OH)~2~D~3~ is well established and occurs at the transcriptional level throu