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Regulation and function of the p53 tumor suppressor protein

✍ Scribed by Kevin M Ryan; Andrew C Phillips; Karen H Vousden


Book ID
114309260
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
568 KB
Volume
13
Category
Article
ISSN
0955-0674

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## Abstract The p53 tumor suppressor protein is a key transcription factor that regulates several signaling pathways involved in the cell's response to stress. Through stress‐induced activation, p53 accumulates and triggers the expression of target genes that protect the genetic integrity of all ce