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Regulation and function of immediate-early genes in the brain: Beyond neuronal activity markers

✍ Scribed by Hiroyuki Okuno


Book ID
116778295
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
559 KB
Volume
69
Category
Article
ISSN
0168-0102

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## Abstract Electrical activity shapes development of the nervous system, presumably in part by regulating gene expression. A set of regulatory genes, immediate early genes (IEGs), which are responsive to a number of extrinsic cellular stimuli have been proposed to play a role in coupling such acti

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## Abstract The immediate‐early gene __Zif268__ is a member of the Egr family of inducible transcription factors. Data from gene expression studies have suggested that this gene may play a critical role in initial triggering of the genetic machinery that has long been considered a necessary mechani