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Regulated Delivery of Therapeutic Proteins After in Vivo Somatic Cell Gene Transfer

✍ Scribed by Ye, X.

Book ID: 121160464
Publisher: American Association for the Advancement of Science
Year: 1999
Tongue: English
Weight: 207 KB
Volume: 283
Category: Article
ISSN: 0036-8075
DOI: 10.1126/science.283.5398.88

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## Abstract ## Background Hemophilia B is an X‐linked bleeding disorder that results from a deficiency in functional coagulation factor IX (hFIX). In patients lacking FIX, the intrinsic coagulation pathway is disrupted leading to a lifelong, debilitating and sometimes fatal disease. ## Methods W